Àá½Ã¸¸ ±â´Ù·Á ÁÖ¼¼¿ä. ·ÎµùÁßÀÔ´Ï´Ù.

¹æ»ç¼±Á¶»ç°¡ ¹é¼­ÀÇ Ä¡ÁÖÁ¶Á÷¿¡ ¹ÌÄ¡´Â ¿µÇâ¿¡ °üÇÑ ½ÇÇèÀû ¿¬±¸

AN EXPERIMENTAL STUDY ON THE EFFECTS OF Co-60 IRRADIATION IN THE RAT PERIODONTIUM.

Ä¡°ú¹æ»ç¼± 1986³â 16±Ç 1È£ p.41 ~ 48
¾öÀμ®, ±èűÇ,
¼Ò¼Ó »ó¼¼Á¤º¸
¾öÀμ® (  ) - °æÈñ´ëÇб³
±èűǠ(  ) - °æÈñ´ëÇб³ Ä¡°ú´ëÇÐ Ä¡°ú¹æ»ç¼±Çб³½Ç

Abstract

ÀúÀÚ´Â µÎ°æºÎ ðþåË Ä¡·áÀÇ ÀÏȯÀ¸·Î »ç¿ëµÇ´Â ¹æ»ç¼±Á¶»ç°¡ Ä¡¾ÆÀÇ À¯Áö ¹× °æÁ¶Á÷ Çü¼º
°ú Æı«¿¡ °ü¿©ÇÏ´Â ±â´ÉÁ¶Á÷À¸·Î¼­ÀÇ Ä¡ÁÖÁ¶Á÷¿¡ ´ëÇÑ ¿µÇâÀ» °üÂûÇϱâ À§ÇÏ¿©, ±ÕÀÏÇÑ Á¶
°ÇÇÏ¿¡¼­ »çÀ°ÇÑ 120gm ³»¿ÜÀÇ Sprague Dowley°è ¿õ¼º¹é¼­ 20µÎ¸¦ ´ë»óÀ¸·Î l0GyÀÇ ¹æ»ç
¼±À» ÀÏȸ Á¶»çÇÑ ÈÄ, ½ÇÇè 2ÀÏ, 1ÁÖ, 2ÁÖ, 3ÁÖ ÈÄ¿¡ Èñ»ý½ÃÄѼ­ H-EÁß¿°»ö, van Gieson¿°
»ö, PA-ACH Çü±¤¿°»öÀ» ½ÃÇàÇÏ¿© °üÂûÇÑ ¹Ù, ´ÙÀ½°ú °°Àº °á·ÐÀ» ¾ò¾ú´Ù.
1. ¹é¾ÇÁú¾Æ¼¼Æ÷¿Í °ñ¾Æ¼¼Æ÷´Â ½ÇÇèÃʱ⿡ Á¡Â÷ ¼Ò½ÇµÈ ÈÄ, ½ÇÇè 3ÁÖÈÄ¿¡ ¹é¾ÇÁú°ú Ä¡Á¶°ñ
¿Ü¿¬À» µû¶ó Àç¹è¿­µÇ¾úÀ¸³ª ÆÄ°ñ¼¼Æ÷´Â °ÅÀÇ ¿µÇâÀ» ¹ÞÁö ¾Ê¾Ò´Ù.
2. Ä¡ÁÖÀδ볻ÀÇ ¼¼Æ÷´Â Á¡Â÷ À§ÃàµÇ°í º¯¼ºµÇ¾î ¼¼Æ÷¼ö°¡ °¨¼ÒµÇ¾úÀ¸³ª, ½ÇÇè 3ÁÖÈÄ¿¡´Â
°ÅÀÇ Á¤»óÀ¸·Î ȸº¹µÇ¾ú´Ù.
3. Ä¡ÁÖÀδ볻ÀÇ ±³¿ø¼¶À¯´Â Á¡Â÷ ÁÖÇàÀÌ ºÒ±ÔÄ¢ÇØÁ³°í ¼¶¼¼ÇØÁ³À¸¸ç ÀÌÀÇ ¾çµµ °¨¼ÒµÇ¾ú
´Ù.
4. Ä¡ÁÖÀδ볻ÀÇ Ç÷°üÀº Ãʱ⿡ Á¡Â÷ °¨¼ÒµÇ¾úÀ¸³ª, ½ÇÇè 2ÁÖÈĺÎÅÍ ´Ù½Ã Áõ°¡µÇ¾úÀ¸¸ç ½Ç
Çè 1ÁÖÈÄ¿¡ µ¿¸ÆÀÌ Æı«µÇ¾î Á¶Á÷³»¿¡ ³ªÅ¸³­ ÃâÇ÷¼Ò°ßÀº ½ÇÇè 3ÁÖÈıîÁöµµ Áö¼ÓµÇ¾ú´Ù.
5. Ä¡ÁÖÀδ볻ÀÇ ´ç¿øÀº Á¡Â÷ Áõ°¡µÇ¾î ½ÇÇè 1ÁÖÈÄ¿¡ ¹é¾ÇÁúÃþÀÇ ±âÁú³»¿¡ ´Ù·®ÀÌ Àú·ùµÇ
¾úÀ¸³ª ½ÇÇè 3ÁÖÈÄ¿¡´Â °ÅÀÇ Á¤»óÀ¸·Î ȸº¹µÇ¾ú´Ù.
#ÃÊ·Ï#
It is known that radiation therapy is a kind of treatment choices of the maxillofacial
tumors. This study is designed to investigate the irradiation effects on rat's periodontal
tissues as functional tissues which relate to tooth-support, hard tissue formation and
destruction. 20 rats (Sprague-Dowley branch, male) were devided into control group of 4
and experimental groups of 16. Experimental group was singly exposed to Co-60
irradiation with 10 Gy in the head and neck region. Animals were sacrificed on 2 days,
1 week, 2 weeks and 3 weeks after the irradiation. The specimens were observed by
histopathological examination employing H-I stain, van-Gieson stain and PA-ACH
fluorescent stain.
The results were as follows:
1. Cementoblasts and osteoblasts were gradually lost and rearranged along the
external surfaces of the cementum and alveolar bone, but osteoclasts were almost not
affected.
2. The cell numbers of the periodontal ligament were decreased due to the cellular
atrophy and degeneration, but recovered almost normally on the 3rd week after
irradiation.
3. The collagen fibers within the periodontal ligament were irregularly oriented,
became finer and decreased in number.
4. The vessels of the periodontal ligament were decreased at the initial stage but
increased again on the 2nd week after irradiation, and the hemorrhagic appearances,
occurred within the tissues, due to the arterial destruction, were lasted until 3 weeks
after irradiation.
5. The glycogen within the periodontal ligament was gradually increased and stored in
the matrices of the cemental side on the 1st week after irradiation, but recovered almost
normally on the 3rd week after irradiation.

Å°¿öµå

¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸

  

µîÀçÀú³Î Á¤º¸